Trimediazine Plain Oral Powder 50g Sachet - Pack 10


Trimediazine Plain Oral Powder is indicated for usein the treatment of bacterial diseases in horses, including upper andlower respiratory tract infections, alimentary tract infections and infectedwounds.

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Trimediazine Plain Oral Powder is a white broad spectrumantibacterial powder for mixing with animal feed.

For oral administration in the feed, .To be given at a rate of 30mg combined active ingredients per kg bodyweight.

Mix with a small quantity of feed. Each 50g sachet provides a daily dose for a 500kg horse.

The dose may be administered daily, or divided and administered at 12 hourly intervals, for 5 days.


It is recommended that other feed be withdrawn until medicated feed has been consumed.

Each sachet containsTrimethoprim 5% w/w and Sulfadiazine 25% w/w.

Contra-indications, warnings, etc

Do not use in horses with severe liver parenchymal damage or kidney damage or known sulphonamide sensitivity or horses with blood dyscrasias.

To avoid the possibility of crystalluria, adequate water intake is essential.

Do not exceed 7 days continuous treatment.

The use of Trimediazine Plain Oral Powder in horses under 1 year old should be avoided.

In the rat and rabbit, trimethoprim/sulfadiazine combinations did not produce any foetal abnormalities at doses of up to 600mg/kg, although minor effects on skeletal development were seen below this level. As no studies have been conducted in horses, use on pregnant mares should be avoided.

When administered to lactating females, small amounts of trimethoprim and sulfadiazine are present in the maternal milk. Since no studies have been reported on the effects of Trimediazine Plain on the development of new born foals, it would be prudent not to feed very young foals with milk obtained from mares being treated.

As there is no specific antidote, in case of overdose, treatment should be symptomatic.